Struggles of Weight Loss and Weight Regain
Talking about how a patient feels after weight loss: surely extremely happy and joyous, and in a sort of "know-it-all" state of mind on how not to gain weight. But what they do not understand is that, apart from psychological changes, they face biological and physiological changes during their weight-loss state which they fail to conceive, and that is what drives the weight regain.
This is exactly why we see the same weight loss patients regain weight, and that is demoralizing in itself; it is very common for such patients to blame their own resolve. That is precisely why it is of utmost importance to understand the biologic defense system of body fat mass, to understand the fat regain occurrence, and it is an essential step in helping such patients maintain long-term weight-loss results.
So far, even the best lifestyle interventions show weight regain, usually observed after 1 year. When we add any type of physical activity to diet, it gives more optimal results than diet alone. Even then, diet alone or diet along with exercise are both challenged by weight regain. Over 20 studies on "long-term weight loss" found that more than half of the lost weight is regained within 2 years and almost 80% of the lost weight is gained back in 5 years. Isn't that a mood damper!
To understand the phenomenon more, we first need to know about the hormones that drive hunger and satiety, called Leptin and Ghrelin. Some of you might have already heard of them. To simplify: Leptin decreases your hunger (increases the feeling of fullness), while Ghrelin increases hunger (now you know the real villain). The problem is that when we lose weight, these hormones change too. Many research studies showed that when a person is in the process of losing weight, they are also losing Leptin. One study found that in 10 weeks the body loses almost 13% of weight, but Leptin levels (remember, the one telling your brain that you're full?) fall by up to 64%, and even when weight loss is 8% at 62 weeks, Leptin is still reduced by 35%. Don't forget that when Leptin levels fall, your body feels starved. So with the decrease of Leptin, Ghrelin increases, because it's the hunger hormone; it makes you feel hungry because the signal your brain is receiving is "starvation mode on". So the patient eats more, and not surprisingly, the study found an increase in patients' appetite due to weight loss. A weight loss patient is out of the frying pan but into the fire, because now they have changes in both appetite/food intake regulation and energy expenditure that favor weight regain. (So much for the best weight loss treatment in Lahore, Pakistan.)
Now we have to understand and accept that the more time passes, the more behavioral changes take place: physical activity gets less and less, eating habits and food itself change, and excessive mobile usage, computer games and even global warming all play a key role in promoting obesity and create an "obesogenic environment". This is not to say that we don't have some "successful losers" who have maintained weight loss over 10 years, as per data from the National Weight Control Registry (NWCR), which was founded in 1993 to identify successful losers, or what we call weight-loss maintainers, and to study the strategies used to achieve and maintain weight loss. You want the best weight loss treatment in Lahore, Pakistan? Now you know where to look and what to look at.